Learn more about current, enrolling, and completed clinical trials for the NPC community
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Therapies in a current clinical trial

Arimoclomol

Sponsoring Organization: Orphzyme

Phase: Completed; not recruiting

Expanded Access: Yes, with restrictions

Contact: Regan Sherman, res@orphazyme.com

Clinical Trial website: https://www.clinicaltrials.gov/ct2/show/NCT02612129?term=orphazyme

Orphazyme

ESB1609

Sponsoring Organization: Escape Bio

Phase: Phase 1 Active; not recruiting

Expanded Access: No

Contact: info@escapebio.com

Clinical Trial website:

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IB1001

Sponsoring Organization: Intrabio

Phase: Completed; not recruiting

Expanded Access:

Contact: Taylor Fields, tfields@intrabio.com

Clinical Trial website: https://clinicaltrials.gov/ct2/show/NCT03759639?term=N-Acetyl-L-leucine

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Trappsol Cyclo

Sponsoring Organization: Cyclo Therapeutics

Phase: Phase 1 Completed; not recruiting

Expanded Access: Yes, with restrictions

Contact: Dr. Sharon Hrynkow,
sharon.hrynkow@cyclodex.com

Clinical Trial website: https://clinicaltrials.gov/ct2/show/NCT03759639?term=N-Acetyl-L-leucine

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Therapies in a completed Clinical Trial

Adrabetadex

Sponsoring Organization: Mallinckrodt Pharmaceuticals

Phase: Completed; not recruiting

Expanded Access Available: No

Contact: Sheila Talafous, Sheila.Talafous@mnk.com

Clinical Trial website: https://www.clinicaltrials.gov/ct2/show/study/NCT02534844?term=Vtesse&rank=1

Mallinckrodt

Miglustat

Sponsoring Organization: Actelion, Edenbridge Pharmaceuticals (generic)

Access: Off label

Contact: Consult your clinician

Clinical Trial website: https://clinicaltrials.gov/ct2/show/NCT00517153?cond=Niemann-Pick+Disease%2C+Type+C&draw=3&rank=17

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